The reason for the increase in blood pressure due to plateau reaction is that the atmospheric pressure in the plateau is relatively lower than that in the plains, so for patients with previous cardiovascular disease, there will be an increase in blood pressure when plateau reaction occurs. In this case, patients should be given oxygen therapy immediately, such as shielding oxygen, oxygen bag oxygen or hyperbaric oxygen chamber system treatment, which can alleviate the situation of high blood pressure increase in plateau reaction. In addition, according to the different degrees of blood pressure, certain antihypertensive drugs should be given for treatment, such as calcium antagonists, ACEI drugs, ARB drugs or diuretics can be applied, and calcium blockers are the preferred antihypertensive drugs for plateau reactions. However, when lowering blood pressure, attention should be paid to slowly lowering blood pressure, and to protect the target organs from secondary damage.