The treatment of chondromalacia patella plus meniscus injury mainly depends on the severity of the patient’s condition. In clinical practice, it is mostly divided into general treatment, drug treatment such as ibuprofen, physical treatment such as localized hot compresses and surgical treatment. 1. General treatment: In the case of chondromalacia patella and meniscus injury, it is recommended that patients mainly rest and reduce walking to avoid aggravation of knee pain. 2. Drug treatment: For mild patients, when the pain is obvious, non-steroidal drugs such as ibuprofen can be given to relieve the pain. Glucosamine and sodium vitrate injection can also be given to promote the repair of cartilage and meniscus. 3. Physiotherapy: In the acute stage of injury, local cold compresses can be given to the knee joint to relieve pain. In the relief period, local hot compresses, infrared radiation and other physical therapy can be given to promote local blood circulation, which is conducive to the relief of symptoms. 4. Surgery: mostly used for patients with serious condition and ineffective conservative estimation, arthroscopic cartilage lesion resection, meniscus repair or resection can be given in the clinic. It is recommended that patients go to the hospital, complete the auxiliary examination, in order to clarify the condition, the professional physician to give appropriate treatment for the condition, the drug needs to be used under the guidance of a professional physician.