Thigh groove moist itching may be due to physiological factors, generally do not need medication, may also be due to ringworm, eczema, need to use antifungal drugs, glucocorticoid drugs. 1. physiological factors: hot weather, strenuous exercise, wearing heavy and other factors may lead to the local environment hot and humid, there will be itchy skin symptoms, generally do not need medication, it is recommended to increase or decrease the number of clothes, wear breathable clothes, to ensure that the local ventilation, pay attention to the local hygiene, a large number of sweating in a timely manner after the bathing, replacement of clothing. 2. ringworm: due to the fungus caused by infectious diseases, acute phase will have inflammatory oozing lead to the thigh root of the moisture, often conscious itching. Antifungal drugs can be used, such as miconazole, econazole, etc., which can inhibit the synthesis of fungal cell membrane and promote the recovery of the disease. 3. Eczema: Acute eczema can be manifested as herpes mound, blisters, itching and other symptoms, with a tendency to ooze. You can use boric acid solution, eschazopyridine solution cold wet compresses, the use of hydrocortisone, tretinoin and other glucocorticoid drugs for anti-inflammatory, anti-allergy treatment. Thigh groove moist itching may also be due to other factors, it is recommended that patients seek medical attention in a timely manner, under the guidance of the doctor standardized treatment, avoid private medication, so as not to delay the condition.