Multiple Merging Toes of the Foot Separation without Autologous Dermal Implantation is a surgical procedure to separate a patient’s merging toes of the foot. Instead of covering the wounds with the same implants that were used in the past, the separated toes are covered with skin through an artificial dermis to induce the growth of one’s own skin. The procedure is usually performed by a hand and foot surgeon who evaluates the patient’s functional toes based on x-ray findings, selects the functional toes to be preserved, and removes the excess toes. Artificial dermis has now been found to induce skin regeneration and is one of the alternatives to autologous skin, guiding the migration of cells around the wound to replace it. Artificial dermis induced skin regeneration technology has been relatively mature, more widely used in clinical applications, artificial dermis may also lead to the formation of localized scarring, is not yet a complete alternative to autologous skin grafts. If the patient decides to have multiple toes separated without autologous skin grafting, it is recommended to have systematic treatment in a regular hospital.