Urine protein 2 + suggests proteinuria, divided into physiological and pathological two cases, physiological will be self-cure, pathological generally will not be self-cure. 1. Physiological: a small number of patients may have proteinuria after strenuous exercise, after eating a large amount of high-protein food, or during strenuous exercise, and usually return to normal after removing the relevant factors. 2. Pathologic: including nephritis, nephrotic syndrome, etc., most of the patients will not be cured by themselves and need timely treatment. Among the primary glomerular diseases, membrane nephropathy has a small number of patients who can recover spontaneously. Patients with urinary protein 2+ need to go to the hospital in time, under the guidance of professional physicians to clarify the cause, timely treatment, do not delay the condition.