Feeling a sense of pressure and tightness in the middle of the clavicle is common in the following cases: 1. Coronary heart disease: The important blood vessel for blood and oxygen supply to the heart is the coronary artery, which can become severely narrowed or even occluded when affected by atherosclerosis. When patients with coronary heart disease are emotionally stressed, excited, anxious, angry, frightened or strenuous exercise, myocardial oxygen consumption increases significantly, but due to the existence of serious lesions in the coronary arteries, they cannot supply blood and oxygen to the heart in a timely and adequate manner, causing insufficient myocardial blood supply and inducing symptoms of chest tightness, shortness of breath, tightness in the precordial area and even angina pectoris; 2. Skin lesions: such as skin injuries and infections, including herpes zoster, scratches, etc., will appear pressure and tightness in the middle of the clavicle; 3. Other lesions: if there is chondromalacia, intercostal neuralgia, etc., it will also manifest as pressure and tightness in the middle of the clavicle. If patients cannot identify themselves, it is recommended to go to the hospital in time to be evaluated and judged by professional doctors.