1.In the first step of drug loading, if you do not hold the DuPao device vertically, it will cause the dose of drug loading to be reduced and affect the efficacy. 2.Try to screw the handle to the end (hold the middle part of the DuPao vertically and rotate the base) and then return to the original position, so that a dose of medicine is added to the inhaler; there is no indication of screwing in that direction first and then in that direction; generally rotate to the end first and then to the end. 3.In addition to unpacking the new package, the 1st time you use it, you need to rotate it 2 times for initialization; later, when loading the medication, you only need to rotate it 1 time, and multiple rotations will all lead to wasted medication. 4.When the filling is completed, do not shake the medicine bottle; if the inhaler is inverted after the filling is completed, the inhaled dose will be lost and it is recommended to refill the medicine. 5.Do not exhale into the inhaler; inadvertently exhaling into the DuPont inhaler may result in loss of inhaled dose, and it is recommended to refill and inhale the medication. 6.Incorrect inhalation action, no forceful deep inhalation, directly affect the actual dose of inhalation. 7, loading 1 time, feel that the inhalation strength is not enough, need 2 or more times to inhale; 2 times inhalation to give the drug, can lead to uneven deposition of the drug dose, synergy can not be fully developed; need to practice more, as much as possible in one breath. 8, when the drug is close to running out, do not pay attention to the tips on the device; the dose indicator window of the DuPao device can show how much dose is left, with a digital marker for every 20 inhalations; when the indicator window appears red, it indicates that there are 10 inhalations left; when the red marker 0 reaches the middle of the indicator window, it indicates that the drug has been used up. 9.When the red mark 0 reaches the middle of the indicator window, indicating that the drug has been used up, if you shake the device, there will be a ringing sound, which is generated by the built-in desiccant, do not think there is still drug to continue the “empty suction” treatment. 10.After each use, wipe the outside of the nozzle with a dry cloth or paper towel, and do not use water or liquid to scrub the nozzle. 11, after use, please cover the protective cap, do not twist the nozzle at will, forbid to disassemble at will. 12, continuous, fixed drug use time interval, the best efficacy, the general initial treatment of morning and evening each time the drug; later according to the control situation under the guidance of the doctor gradually adjusted, if the dose is reduced to once a day, it is recommended to inhale before bedtime.