Herpes causes neuralgia is caused by varicella-zoster virus invasion of nerves resulting in ganglion inflammation, necrosis, neuralgia slowly recovered manifested as pain, itching and other symptoms gradually reduced until disappearance. Herpes is a skin disease caused by herpes simplex virus or varicella-zoster virus infection, which is prevalent in immunocompromised people, and manifests as unilateral banding of blisters and erythema on the extensor nerves, accompanied by varying degrees of neuralgia. Herpes patients after active antiviral treatment, analgesic treatment, nutritional nerve treatment, most patients have a better prognosis, manifested by the symptoms of rash and pain can be relieved, the itching and pain in the unlesioned areas and related radiating areas gradually disappear; however, some patients may have residual neuralgia, which affects the patient’s life treatment. It is recommended that patients with herpes seek timely medical treatment, standardized treatment under the guidance of the doctor, so as not to delay the condition.