Patients with uterine fibroids can take progesterone. Uterine fibroids are an estrogen-dependent disease, mainly related to the level of estrogen in a woman’s body. If the estrogen is higher, the chance of having fibroids will be higher and the fibroids will grow faster, and vice versa, the chance is lower and the growth is slower. Progesterone is a kind of progestin, progesterone can counteract estrogen, so it can treat fibroids, and to a certain extent can prevent excessive growth of fibroids, so patients with fibroids can take progesterone. Patients with uterine fibroids should be aware that they should not eat foods or drugs containing estrogen, such as Tocopherol and Clomid, because they contain estrogen and the growth of fibroids will be faster after they take them. At the same time, patients must eat less estrogen-containing foods such as soy isoflavones and honey.