Nucleic acid testing includes a variety of methods, poking the nose or throat or their collection methods are possible. Currently, the common nucleic acid testing methods mainly include the following: 1. Nasopharyngeal swab test: mainly the sampling tool is sent into the nasal cavity to collect the secretions from the nasopharynx as specimens for testing, which can be used for sampling during routine screening; 2. Oropharyngeal swab test: the main sampling tool is sent into the oral cavity to collect secretions from the oropharynx as a specimen for testing, which is currently the most widely used, and is used for sampling in large-scale population screening; 3. Lower respiratory secretion test: mainly collects respiratory secretions of the examinee, such as sputum, alveolar lavage fluid, etc., as a specimen for testing; 4. Anal swab test: Anal swab test may be performed for some subjects who show digestive symptoms, such as vomiting, diarrhea, and so on; The specific choice of which test is mainly based on the subject’s specific personal situation, related symptoms, and usually need to follow the advice of a medical professional.