1. Etiology of genital herpes: 85% of first infections and more than 98% of recurrent damage are caused by HSV-2, and genital herpes caused by HSV-1 is beginning to increase due to changes in sexual behavior. In some developed countries, up to 40% of female anal genital herpes is caused by HSV-1. In the genital area, HSV-1 infection causes much fewer recurrences than HSV-2. 2, transmission of genital herpes: Genital herpes is transmitted by skin-to-skin contact, usually during sexual activity, with an average incubation period of 6 days (2 to 20 days). active damage caused by HSV-2 contains live virus and is contagious. 3. Asymptomatic detoxification of herpes virus: Patients with recurrent genital herpes may have asymptomatic detoxification between episodes. Asymptomatic detoxification can occur at several anatomical sites simultaneously (vagina, cervix, and rectum) and can occur from normal-looking intact skin and mucous membranes. Transmission of genital herpes occurs most often during subclinical, or unrecognized episodes or when the infected person is in asymptomatic detoxification. Barrier contraceptive methods can reduce transmission. The clinical spectrum of primary HSV-2 infection is broad and can range from completely asymptomatic to severe genital ulcers. Only 57% of new HSV-2 infections are symptomatic. 4, primary infection and non-primary infection: primary infection, patients for the first time, can be divided into primary infection and non-primary infection. Primary infection: Infected patients have no history of herpes simplex and negative serological tests for HSV antibodies. Non-primary infection: There is serological evidence of previous HSV infection, and the symptoms are milder than those of primary infection. 5. Clinical manifestations: Primary genital herpes infection can manifest as a severe systemic disease. Clusters of blisters and vesicles appear in the vagina, rectum or penis, and new blisters occur continuously within 7-14 days, and the vesicles and ulcers are often painful. The inguinal lymph nodes are symmetrically enlarged, and fever and flu-like symptoms may be present. Women may complain of vaginal pain and difficulty urinating, and the entire course of the disease may last 3 weeks or longer. People with previous HSV-1 infection have milder symptoms when first infected with HSV-2, similar to recurrent herpes, but the course of the disease may be several days longer. In gay men, severe proctitis can occur if the inoculation is in the rectal area. There is severe anorectal pain, anal discharge, and a feeling of urgency. Some patients have perianal blisters or ulcers, and the anal canal may have extensive erosion of the mucosa. Recurrent genital herpes, in both men and women, is a common site of genital herpes recurrence in the upper buttocks. The natural course of untreated recurrent genital herpes is poorly studied, and the frequency of recurrence remains the same over several years or less, and decreases over longer periods of time (more than 5 years), especially in those patients who have used suppressive therapy. 6. atypical genital herpes: atypical clinical manifestations are very small vesicles or linear fissures in the genital skin, with damage occurring in the mucous membranes of the vulva, vagina and cervix, as well as in the skin of the penis and vulva. People with atypical genital herpes are infectious and are an important factor in the increase of new HSV-2 infections. 7. Laboratory tests: These include serological methods, culture methods, and cytological methods. Serological methods can be used for epidemiological investigations to estimate infection in the population and cannot be used for clinical diagnosis. primary HSV infection can be demonstrated when HSV antibody titers change from negative to positive, but serum antibodies do not increase in the event of a recurrence. The actual fact is that you can be able to get a good deal on your own, and you will be able to get a good deal on your own. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. For patients with severe symptoms but few recurrences or severe psychological complications, intermittent treatment can be given. Effective treatment must be administered at the earliest possible stage of an episode. Patients must be given medication prior to a relapse so that they can begin treatment when the first symptoms appear. Suppressive treatment of recurrent genital herpes apparatus: In patients with frequent recurrences (more than 6 recurrences per year), daily oral viral suppressants can reduce the frequency of recurrences in more than 75% of people with genital herpes infection. Long-term suppressive therapy is very safe and laboratory testing is not necessary. The frequency of recurrence was re-evaluated by discontinuing the drug after 1 year of continuous oral administration. The minimum dose for recurrence suppression varies from person to person. The main drugs commonly used are acyclovir and valacyclovir.