Lipoma is a kind of common benign soft tissue tumor, for the relatively small size of lipoma without adverse reaction, can not be special treatment, regular observation can be, for the larger size of lipoma can be eliminated through surgery. Lipoma is a tumor of normal fat-like tissue, which occurs in the limbs and trunk, and often appears in the neck, shoulder, back, abdomen, arms and other parts of the body. Because lipomas have no specific symptoms, they are easily confused with liposarcoma, epidermoid cysts, and cutaneous cysticercosis. For slow-growing, small-sized lipomas that do not cause discomfort, they usually do not need special treatment, and can be observed and rechecked according to the doctor’s instructions; for large-sized lipomas that cause discomfort or affect the aesthetics of the patient, they can be treated by surgical excision. Various kinds of medication, physical therapy and other methods can not eliminate lipoma. Most of the lipoma patients can be cured after active treatment, and the prognosis is good. It is recommended that the patients keep good mood and healthy life habits, actively cooperate with the doctor’s treatment, and undergo regular checkups.