Popular knowledge about “recurrent miscarriage

  If you yourself or your wife have experienced ≥2 consecutive spontaneous miscarriages (including spontaneous abortion, empty gestational sac, embryonic arrest, etc.), then you need to know the following to help you properly diagnose and treat the problem and finally get a healthy baby!
  First, to help you analyze the causes of spontaneous miscarriage occurrence.
  In nature, spontaneous miscarriage is common and may occur in about 25% of pregnancies, the vast majority of which are caused by chromosomal abnormalities in the baby by chance.
  So, if you are healthy and have experienced only 1 miscarriage, please do not worry too much and try to get pregnant again after 3-6 months of contraception to welcome the new life!
  However, if you have experienced ≥2 consecutive spontaneous abortions (medically known as “recurrent miscarriages”), then you need to have a full medical examination.
  Then you need to do a comprehensive screening for the causes of miscarriage:
  1. Chromosome examination of both spouses or chromosome examination of the miscarried embryo is also very meaningful.
  Because chromosomal abnormalities are the most common cause of miscarriage, accounting for about 3-5%;
  2. Transvaginal ultrasound or hysteroscopy is done to see if there is something wrong with the uterus.
  Including: uterine malformation, uterine fibroids, adenomyosis, uterine adhesions are common causes, accounting for about 5%.
  3, immune, endocrine examination.
  Including: sex hormones, thyroid function and antibodies, anti-cardiolipin antibodies, lupus antibodies, blood sugar, insulin, etc. If the above is not normal is required for treatment.
  4. If available, genetics tests for embolism can be done.
  Including: FVL, activating protein C resistance, pro-coagulation gene mutation and protein S defect detection.
  5, the male side of the examination: semen routine, if necessary also do sperm morphological examination and sperm DFI test.
  6.In addition, you should make sure that your living and working environment is free of toxic exposure and that you have no bad habits.
  Including: exposure to ionizing radiation, organic solvents, mercury, lead, etc.; drinking alcohol, smoking (including second-hand smoke), excessive coffee and other bad habits; if there are you should avoid as much as possible.
  But using computer, watching TV, doing ultrasound, electric blanket, non-strenuous exercise, working at work, the food we often eat will not cause miscarriage, long-term bed rest is also meaningless, these misconceptions will only increase the psychological burden, scientific understanding of miscarriage, good psychology is very important for your future pregnancy.
  7.After the above checkup, you may have found the cause of your disease, and you only need to treat the symptoms to get cured!
  If you can’t find the cause of your miscarriage after the above screening, don’t worry, it’s true that 60% of patients can’t find the cause, don’t be discouraged because as long as the above tests are normal, your next pregnancy will still have 70% chance of being normal and no miscarriage will occur. At this time, you must follow the advice of your specialist and not to rush to the doctor, there are some tests and treatments that are not necessary, as follows:
  (1) Anti-sperm antibodies, anti-endometrial antibodies, anti-ovarian antibodies, etc.
  (2) Tests for viruses or bacteria.
  (3) Genetic testing for immune factors.
  (4) There are also tests for immune cells and closed antibodies, which are still very controversial and have limited clinical guidance value.
  Finally, to help you develop the right treatment plan: (at this point, you will need to consult with your doctor to individualize your treatment plan)
  Couples with chromosomal, or embryonic chromosomal abnormalities, need to consult with a specialist and you may need PGD (pre-implantation genetic diagnosis, commonly known as third generation IVF).
  For uterine problems, some need to be treated and some don’t, please consult your doctor.
  If you have immune or endocrine problems, you will need medication, please consult your doctor.
  If you are obese, you will also need to lose weight.
  If you can’t find any cause after detailed investigation, you can get pregnant even after six months of contraception, because the probability of not miscarrying again is still greater than the probability of miscarriage, and keeping a good attitude is more important than any treatment!