High C-reactive protein indicates a bacterial infection and needs to be treated with sensitive antibiotics. Commonly used drugs include cephalosporin antibiotics and proprietary Chinese medicines with the effect of clearing heat and removing toxins, such as clearing heat and removing toxins tablets or Shuanghuanglian oral solution. For cephalosporin allergy patients, can be given clarithromycin or clindamycin for treatment, oral administration is not effective, you can choose intravenous infusion of drugs, intravenous infusion of commonly used drugs are ceftazidime injection or clindamycin injection, three to five days or so C-reactive protein can return to normal. If patients with coronary heart disease have high C-reactive protein, they need to be actively hospitalized for standardized treatment, which mainly focuses on nutritive myocardium and vasodilatation, and commonly used medications include Danghong injection, Thrombotoxin injection, oral coenzyme Q10, or stabilized heart particles.