The main reason for the soreness of the legs and stomach the next day after drinking alcohol is that the blood circulation in the legs is damaged after drinking alcohol, which leads to the clinical manifestation of soreness and dysfunction in the legs. Each person’s ability to metabolize alcohol is not the same, the next day after drinking alcohol, sore legs and stomach, because alcohol is metabolized in the body to acetaldehyde, and then metabolized to acetic acid, acetaldehyde is harmful to the body, acetaldehyde metabolism to acetic acid enzyme content is reduced or activity, resulting in the accumulation of acetaldehyde. The enzyme that metabolizes acetaldehyde to acetic acid is low or inactive, leading to a buildup of acetaldehyde. The body’s metabolism is weakened after drinking, leading to a buildup of lactic acid, which is the cause of leg and stomach pain. Therefore, within 48 hours after drinking, pay attention to rest, drink more water, you can take Chinese medicine acupuncture, gua sha approach to promote the recovery of the symptoms of sore legs and stomach, pay attention to adequate rest, elevate the affected limbs, to ensure that the blood circulation is smooth, you can orally take some of the swelling, anti-inflammatory, analgesic medication for symptomatic treatment. If after the above strict standardized treatment, the symptom improvement is not obvious or progressive aggravation, you can perform the lower extremity vascular ultrasound to see whether the formation of lower extremity venous thrombosis, if the lower extremity venous thrombosis, it should be dealt with in time.