Painful skin rashes can be caused by diseases such as herpes zoster, contact dermatitis, folliculitis, or other diseases such as insect bite reactions. 1. Herpes zoster: Herpes zoster is mainly caused by varicella-zoster virus infection, and patients will experience pain, pimples, papules, blisters and other symptoms. In addition, patients with herpes zoster will also experience symptoms such as fatigue, low-grade fever and headache. 2. Contact dermatitis: contact dermatitis is mainly an allergic reaction caused by skin contact with exogenous substances, and the main symptoms of patients are erythema, dense papules, edema, itching, swelling and pain, and blisters, burning and other symptoms. 3. Folliculitis: the most common cause of folliculitis is bacterial infection, the patient’s main symptoms are red papules, pain, itching, etc., as well as pus, fever and other symptoms. 4. Other: Insect bite reaction, eczema and other diseases can also lead to the phenomenon of skin rash pain. Patients with symptoms of painful skin rashes should consult a doctor for timely examination and treatment as prescribed by the doctor.