The difference between retinal lentigines and FMS includes differences in etiology, symptoms, and treatments. 1. Etiology: peripheral retinal tears in retinal tears are mainly associated with high myopia, and macular tears can be caused by trauma, macular aging, and ocular inflammation. Flying mosquito syndrome includes physiological and pathological, physiological is mainly related to age, pathological can be due to vitreous blood, vitreous inflammation, parasites and so on. 2. Symptoms: peripheral retinal fissure can have symptoms such as fixed flash sensation and black shadow fluttering, while macular fissure can have symptoms such as decreased visual acuity and distorted vision. Flying mosquito is mainly manifested as a small black shadow in front of the eyes, which may be accompanied by a flashing sensation. 3. Treatment: peripheral retinal tear can be treated with laser, macular tear or peripheral retinal tear leading to retinal detachment requires surgical treatment. Physiological Aedes aegypti usually does not need special treatment, while pathological Aedes aegypti needs to be treated according to the cause of the disease. If it is caused by vitreous hemorrhage, hydroxybenzene sulfonylamine and antenocin can be used to stop the bleeding according to the doctor’s instruction. The above is a part of the difference between these two diseases, specific differential diagnosis is recommended to consult a doctor in time, by a professional doctor for diagnosis.