Glomerular filtration rate 60ml/min is less likely to be stable for life if it is due to chronic kidney disease and can develop into uremia as the disease progresses; if it is due to acute renal failure, it may remain stable or even return to normal after correcting the causative factors. Glomerular filtration rate of 60 ml/min is chronic if it is chronic, it belongs to chronic kidney disease stage 3, which is generally progressive, and hyperglycemia, hypertension, proteinuria, and hyperuric acid caused by the underlying disease will lead to the progression of renal function. Treatment is based on controlling the primary disease and related complications, and try to delay the disease progression, which can develop into uremia and need renal replacement therapy in the later stage. Glomerular filtration rate of 60ml/min, in case of acute renal failure, commonly seen in low blood pressure, hemorrhage, dehydration, use of nephrotoxic drugs such as contrast media, heart failure, severe infections, etc., which may make the organism’s blood volume insufficient or reduce the blood supply to the kidneys, and the renal function deteriorates sharply. After active and effective treatment, renal function may be stabilized or even return to normal. For patients with glomerular filtration rate of 60ml/min, it is recommended to consult the nephrology department of regular hospitals in time to find out the cause and carry out standardized treatment under the guidance of doctors.