There are actually four main symptoms of childhood leukemia, which are fever, anemia, bleeding and enlarged liver and spleen lymph nodes. In the early stage of childhood leukemia, more than 50% of children will have a fever, which can be high or low, and the cause cannot be found. Some children also have respiratory tract infections, such as a runny nose and cough, which are often misdiagnosed by parents who think it is a cold. In addition, nearly 40% of children’s first symptom will appear bleeding, bleeding parts can be all parts of the body, there can be purpura, epistaxis, bleeding gums, etc.; the larger girl is to have menstrual period, appearing excessive menstruation; some children may suddenly appear to see things unclear, i.e., fundus hemorrhage; individual children will suddenly have a headache, vomiting, which is the phenomenon of intracranial hemorrhage; there are also some children, the Parents find swollen nodes in their neck lymph nodes or axillary lymph nodes, which are actually enlarged lymph nodes. In these cases, you should go to the hospital in time, the doctor will carry out physical examination, as well as blood routine, peripheral blood smear examination, will find that the value of white blood cells in the blood is very high, may reach (30-50) × 10^9 / L, platelets drop or hematocrit decrease such a situation, at this time, the doctor may recommend bone marrow aspiration examination, bone marrow aspiration is actually a relatively common and safe method, the child may be afraid, afraid of the method, but the child may be afraid of the method. Bone marrow aspiration is actually a common and safe method, children may be afraid, but parents must understand that this is a necessary test, so they should understand and cooperate.