Loss of elasticity of blood vessels is usually considered to be a result of atherosclerosis, which is usually due to dyslipidemia, hypertension and other conditions. Usually healthy arteries have elasticity, while atherosclerosis patients affected arteries, there will be localized lipid aggregation, fibrous tissue proliferation on the calcium deposits, and ultimately the formation of plaque. With the passage of time, the arterial wall will harden, so that the blood vessels gradually lose elasticity, mainly affecting the coronary arteries, renal arteries, cerebral arteries, carotid arteries and so on in the body. Atherosclerosis is a slow progressive disease, some patients may have started in childhood, but its exact cause is not clear, mostly considered to be related to dyslipidemia, diabetes mellitus, hypertension, genetics and other factors. Conditions such as reduced physical activity, smoking, poor dietary habits, and obesity can also increase the risk of atherosclerosis. It is recommended that patients lose elasticity of blood vessels in a timely manner under the guidance of a doctor to find out the cause of the disease, and take targeted treatment to avoid delaying the condition.