High low pressure in middle-aged people is mainly related to the following factors: 1. Increased peripheral vascular resistance, in this case the resistance to blood flow in the aorta to the periphery will increase, and the amount of blood remaining in the aorta during diastole will be more, thus causing increased low pressure. Calcium antagonists can be chosen to reduce this peripheral vascular resistance, commonly used drugs such as nifedipine controlled-release tablets, amlodipine, felodipine extended-release tablets, etc. 2, when the heart rate increases the heart diastolic time is relatively shortened, the blood flow to the periphery during the diastolic period of the heart will be reduced, the amount of blood remaining in the aorta will increase, diastolic pressure, that is, low pressure will increase, taking drugs to slow down the heart rate relatively The diastolic period is prolonged, which helps to improve the symptoms of high blood pressure. Commonly used heart rate slowing drugs, such as metoprolol extended-release tablets, bisoprolol, carvedilol, etc.