After metastasis-free resection of gastric cancer, there is a risk of recurrence. Reducing recurrence rate not only depends on standardized radical surgery, but also related to the malignant degree of the tumor itself, stage, gene expression, drug sensitivity, autoimmunity and other factors. Early gastric cancer without metastasis can be treated with simple radical surgery in most cases, and patients only need to have regular checkups, and the cure rate is relatively high. Some types of gastric cancer with high malignant degree, such as indolent cell carcinoma, are prone to metastasis even at early stage, and it is difficult to diagnose whether there is metastasis or not, so patients have to undergo chemotherapy, targeted therapy, immunotherapy and other related treatments to reduce the risk of recurrence after surgery. In addition, gastric cancer often has corresponding predisposing factors, such as Helicobacter pylori infection, diet, micronutrient deficiencies, etc. If these causes are not improved, gastric cancer may recur. Therefore, early gastric cancer should be followed up for a long period of time after surgery, and regular checkups should be conducted to find out whether there is any recurrence as early as possible.