Alcohol consumption by both spouses during pregnancy preparation may cause intrauterine growth retardation, central nervous system dysfunction, facial and body parts malformations, and lower intelligence than ordinary children after birth. In men, alcohol can adversely affect the formation of sperm, leading to problems such as abnormal sperm development, reduced number and vitality, which can affect the chances of conception; excessive alcohol consumption can also cause sexual dysfunction. The sperm production cycle of men is three months, which means that in order to avoid the risk of disease, men should quit smoking and drinking three months before preparing for pregnancy. During the preparation period, both smoking and alcohol should be stopped to ensure that the chances of conception will not be affected and the fertilized egg will not be affected and the safety of the fetus will not be endangered. It is also important to pay attention to couples taking folic acid tablets at the same time to prevent congenital neural tube abnormalities in the fetus, not to stay up late, pay attention to a balanced diet and nutrition, and exercise to enhance physical fitness to prepare for conception.