Pimples on the back can be a sign of acne, folliculitis and other conditions, or boils. The treatment is based on the cause of the disease, through lifestyle modification, medication, and other methods. 1. Acne: Acne may appear as pimples, pustules or nodules on the back. Medications such as retinoic acid cream, adapalene gel, and fusidic acid cream can be applied to the acne area, followed by oral isotretinoin and vincristine in severe cases. If a large pustule has been formed, incision and drainage surgery should also be carried out. 2. Folliculitis: a red, swollen bump with white dots on the top will appear on the back. Bacterial folliculitis needs to be treated with medications such as erythromycin ointment and mupirocin ointment, and in severe cases, oral antibiotics such as roxithromycin. Fungal folliculitis can be treated with drugs such as amorolfine, and avoid squeezing with hands to avoid infection. 3. Boils: manifested as hemispherical bumps with obvious pain. It can be treated with ichthyol ointment and other medications, and in severe cases, the boil can be surgically removed after the inflammation subsides. The above medications should be used in accordance with the doctor’s instructions, do not self-medicate. Patients with back acne are advised to seek medical attention to identify the cause and standardize treatment under the guidance of a doctor.