The swelling of the lips after sleeping may be caused by the following: First, it may be physiological edema, which may be caused by the intake of too much water before going to bed, and the swelling of the lips or the face that accompanies it, which will naturally subside when the blood circulation is restored by activity or local warm compresses after getting up. Secondly, it may be caused by local allergies, such as sleeping beds and pillows with mites to stimulate the lips, and allergic reactions, or it may be the use of cosmetics, facial cleansers and other chemical substances before going to bed, stimulating the lips, causing allergic inflammatory reactions, generally in addition to local swelling, accompanied by local itching.