Severe morning sickness in early pregnancy can be treated with general management and psychological supportive therapy, rehydration, vitamin B6 and other medications. General treatment 1. Severe vomiting can take a small amount of meals, avoid eating greasy food, and choose easy-to-digest food such as cereal porridge. 2. Avoid contact with odors and keep the living environment well ventilated. Medication 1. Rehydration: severe vomiting with large amount of fluid loss, glucose, saline and other fluids can be given to replenish the fluid can be added potassium chloride, vitamin C, sodium lactate and other drugs to maintain water electrolyte and acid-base balance. 2. Antiemetic drugs: antiemetic drugs such as vitamin B6 and vitamin B6-doxilamine compound preparation; antiemetic drugs such as iproniazine and metoclopramide. The above drugs need to be used under the guidance of clinicians, and unauthorized use of drugs is prohibited. Most of the patients with severe vomiting can be improved after active treatment, and the vomiting will subside naturally with the increase of pregnancy weeks.