There are several reasons for the development of osteoarthritis of the knee: First, it is related to age, which is a natural process of change and aging, and the articular cartilage is a natural degenerative process. Second, it is related to high-intensity joint activities, including mountain climbing, marathons, and mountaineering, which can cause wear and tear on the joints. There are also occupational factors, including weight-bearing activities, such as porters are more likely to cause degeneration of articular cartilage occupation. Third, weight-related, obese patients are more likely to cause joint wear and tear. Because of the heavy weight, in the normal walking process, the whole body load on the knee joint, can increase the wear and tear of the joint. Therefore, obese patients are especially prone to joint wear and tear and osteoarthritis. In addition, there may be a relationship with heredity. Generally, patients with osteoarthritis in their father’s generation have a higher chance of developing osteoarthritis in the next generation. It is also common to find osteoarthritis in diabetic patients because of the change in arthritic traits. Traumatic osteoarthritis caused by bony trauma is also an aspect. In addition, women, especially older women, develop osteoporosis after menopause, which itself can also cause osteoarthritis.