There is no prescription for osteoarthritis of the knee, and the treatment of osteoarthritis of the knee mainly includes general treatment, drug treatment and surgical treatment. 1. General treatment: For obese people, weight reduction can be carried out to reduce the weight of the knee joint. Daily use of crutches and other supports to reduce the load. Wedge insoles can be used if there is knee inversion or knee ectropion. You can do knee flexion exercise to relieve joint pain. 2. Medication: Non-steroidal anti-inflammatory drugs such as ibuprofen can be used to relieve pain and reduce inflammation. Glucocorticosteroids such as prednisolone can be used for closed treatment, usually for acute inflammation or with peripheral synovitis. Glucosamine and interleukin-1 inhibitors such as bivalirudin can promote cartilage repair. 3. Surgery:Surgery can be performed if conservative treatment is ineffective, and commonly used surgical methods include synovectomy and joint cleaning. If you are diagnosed with osteoarthritis of the knee, you must follow the doctor’s requirements for treatment, and the medication should be in accordance with the doctor’s instructions, do not blindly use prescriptions.