Positive IgG antibodies to herpes simplex virus types 1+2 represent previous infection with herpes simplex virus types 1 and 2. Herpes simplex virus is abbreviated as HSV, and there are 2 subtypes of HSV, namely HSV-1 and HSV-2. HSV-1 mainly causes herpes of the mouth and lips, herpetic eczema, stomatitis, keratoconjunctivitis and other diseases, while HSV-2 mostly causes genital herpes. There are two types of antibodies that can be detected after infection with HSV, IgM for acute infection and IgG for previous infection, so a combination of both types of antibodies is needed to determine the status of HSV infection. If both IgG and IgM are positive, it represents recurrent infection or re-infection of HVS, which needs to be treated with medication such as acyclovir under the guidance of a doctor; if IgG is positive and IgM is negative, it represents previous infection, which does not need treatment. Positive IgG antibody to herpes simplex virus type 1+2 also needs to be combined with the IgM result to determine the infection status and, if necessary, be treated with medication under a doctor’s supervision.