Whether it is better to operate or be conservative in the middle and late stages of gastric adenocarcinoma mainly depends on the condition of the patient, his physical health and the skill level of the doctor. If gastric adenocarcinoma in the middle or late stage has only metastasized to local peritoneum, liver and other parts of the body, and no extensive metastasis has occurred, the patient’s health condition is good, and the doctor’s operation experience is relatively rich, the patient can be considered to undergo surgery to contact the diseased tissues as much as possible. If distant metastasis has occurred, the patient’s body is weak and cannot tolerate surgery, and the local medical condition is not good, the patient can consider receiving conservative treatment such as radiotherapy and chemotherapy (e.g., 5-FU, furazinouracil, mitomycin, etc.) for the time being. Because the condition of each patient with gastric adenocarcinoma in the middle or late stage is different, the best clinical management will also be different. It is recommended to go to the gastrointestinal surgery department of the hospital as soon as possible, and the professional doctors will take into account the specific condition of the patient and make a personalized diagnosis and treatment plan.