Amlodipine benzenesulfonate causes rapid heart rate can be reduced in dosage or co-administered with beta-blockers such as metoprolol to control the heart rate in the normal range. Amlodipine besylate is a dihydropyridine calcium channel blocker, which is mainly used in the treatment of hypertension, and its main adverse effect is that the decrease in blood pressure may reflexively cause a rapid heart rate. If the accelerated heart rate does not cause discomfort or any clinical symptoms, there is no need to deal with, if there are palpitations, chest tightness and other symptoms, it is necessary to adjust the dose of the drug, but if the dose is reduced may not achieve the desired effect of lowering blood pressure, which needs to be co-administered with β-blockers. Beta blockers have negative contraction, negative heart rate and negative conduction effects on the heart, which can control the excessive heart rate, and also can diastole blood vessels and have the effect of lowering blood pressure. If the above methods can not solve the problem of rapid heart rate, it is recommended to consult a cardiovascular internal medicine department, under the guidance of the doctor to rationally use antihypertensive drugs.