Immunoglobulins are usually abnormal in AIDS patients. AIDS is caused by infection with the human immunodeficiency virus, which can lead to damage to the patient’s immune system, resulting in a variety of serious opportunistic infections or tumors. HIV replicates in large numbers in the body, decreasing the number of lymphocytes and compromising the immune system, which may cause a decrease in immunoglobulin levels; if an infection occurs, it may cause a transient increase in immunoglobulin. It is not possible to determine whether or not you have AIDS from a normal immunoglobulin level alone. If HIV infection is suspected, it is important to go to a regular hospital as soon as possible for testing and to take appropriate interventions in a timely manner. If AIDS is diagnosed, treatment should be standardized according to the doctor’s instructions, and regular checkups should be conducted to prevent complications.