Betahistine Mesylate can be taken with Nicergoline, and there is no contraindication to their use. Coadministration is indicated for the treatment of dizziness in the elderly, and it is recommended that the drug should be used under the supervision of a physician. Betahistine mesylate is suitable for Meniere’s disease, vestibular neuritis, vertigo and other diseases caused by dizziness; and nicergoline is suitable for the elderly dizziness, vascular dementia, etc., there is no contraindication between the two drugs, and the same drug is mainly used for the symptomatic treatment of dizziness in the elderly. The adverse reactions of betahistine mesylate are nausea and vomiting, skin rash, prohibited for those who are allergic to the drug; the adverse reactions of nicergoline are mental abnormality, gastrointestinal reaction, skin rash, etc., prohibited for patients who have recently had a myocardial infarction, acute hemorrhage, severe bradycardia, upright hypotension, hemorrhagic tendency and so on. Patients who are unwell should seek medical attention and use the drug under the guidance of a physician.