Miconazole nitrate suppositories are used to treat mycosis fungoides caused by Candida infection and can be used for inflammatory vaginal diseases that may be caused by gram-positive bacterial infections. The reactions that may occur after intravaginal placement of miconazole nitrate suppositories include: 1. Increased vaginal discharge, which is a normal physiological phenomenon due to the dissolution of the drug in the vagina and its mixing with vaginal secretions, does not require special treatment. 2. If the symptoms are mild, it does not affect the continued use of the drug. 3. Allergic reactions, most patients may have mild symptoms, such as hives or abnormal vaginal discharge, but may also cause serious allergic reactions, such as angioneurotic edema.