In addition to viral hepatitis, fatty liver disease has become the second most important liver disease threatening the liver health of the nation and has been recognized as a common cause of insidious cirrhosis. Fatty liver is a common clinical phenomenon rather than an independent disease caused by excessive accumulation of fat in liver cells due to various reasons. Fatty liver is mostly found in the following types of people: obese people, excessive alcohol drinkers, high-fat dieters, people who move less, patients with chronic liver disease and middle-aged and elderly endocrine patients. Obesity, excessive alcohol consumption and diabetes mellitus are the three main causes of fatty liver. Classified according to the degree of histopathological changes in the liver, there are roughly four conditions: 1. Simple fatty liver: the lesions of the liver are only manifested as fatty degeneration of the liver cells. 2. Steatohepatitis: It is an inflammation of hepatocytes that occurs on the basis of steatosis of hepatocytes. 3.Fatty liver fibrosis: It refers to the fibrotic changes that occur around the hepatocytes. 4.Fatty cirrhosis: Fatty cirrhosis is the result of the progressive development of fatty liver disease to an advanced stage. Due to the lack of specific clinical manifestations and laboratory test indicators for fatty liver, and the invasiveness of liver puncture biopsy, ultrasound and CT are now mainly used to diagnose fatty liver. It has been proven that imaging not only screens for fatty liver, but also confirms the diagnosis. Given that ultrasound has the advantages of being economical, rapid and non-invasive in diagnosing fatty liver, regular ultrasound examination of the liver for people at high risk of fatty liver is the best method for early detection of fatty liver. In terms of treatment, first of all, to find out the cause of the disease, such as long-term heavy drinkers should stop drinking; over-nourished and obese people should strictly control their diet; diabetic patients with fatty liver should actively and effectively control their blood sugar. Second, adjust the diet structure, advocate high protein, high vitamin, low sugar, low fat diet. Also, increase exercise appropriately to promote fat consumption in the body. Finally, medication-assisted treatment early detection and active treatment, generally can be cured. According to statistics, there are 15-20 million alcoholics in the world, 10%-20% of whom have varying degrees of alcoholic liver disease. Alcoholic liver disease, three common types of clinical: 1, alcoholic fatty liver is generally asymptomatic, some people can appear weakness, lethargy, loss of appetite, abdominal distension, nausea, vomiting and other manifestations, there will also be obesity, liver enlargement and other signs. 2, alcoholic hepatitis patients often drink a lot of alcohol for a short period of time before the onset, clinical manifestations in addition to the symptoms of alcoholic fatty liver, there are fever, abdominal pain, diarrhea, etc., and there is significant weight loss. Patients may show anemia and neutrophilia, elevated transaminases, increased serum bilirubin and other manifestations. 3.Patients with alcoholic cirrhosis are asymptomatic in the early stage, and may show weight loss, loss of appetite, abdominal pain, fatigue, fever, dark urine and bleeding gums in the middle and late stages. Jaundice, ascites, swelling, upper gastrointestinal bleeding and other symptoms may appear in the decompensated stage of cirrhosis. Laboratory tests may show anemia, decrease in white blood cells and platelets, decrease in serum albumin and increase in globulin. The treatment of alcoholic liver disease is mainly aimed at: reducing the severity of alcoholic liver disease, stopping or reversing liver fibrosis, improving the secondary malnutrition that already exists, and the treatment of alcoholic cirrhosis. 1, abstinence from alcohol; 2, nutritional support and nutritional therapy: patients with alcoholic hepatitis can have secondary protein-calorie deficient malnutrition, which is related to the severity of the disease and the rate of death. Protein should be supplied in priority to dairy and vegetable proteins, fat intake should contain a certain percentage of unsaturated fatty acids, and for patients with dyspepsia, medium-chain fatty acids need to be provided. For chronic alcoholics, intravenous infusion of amino acids, especially branched-chain amino acids, is sometimes required to maintain positive nitrogen balance. 3.Medication: Long-term alcoholics often have vitamin deficiency due to impaired vitamin metabolism in the liver, especially vitamin B1, B6, folic acid and vitamin A and E. Therefore, vitamin supplementation is necessary, especially vitamin B1. The application of antioxidants such as zinc, selenium and vitamin E can effectively treat alcoholic liver disease and reduce the death rate. Drug-induced hepatitis is also attracting more and more attention. According to clinical statistics, there are more than 500 kinds of drugs that cause liver damage, and liver damage from Chinese herbal medicine is becoming more and more common. Two important factors of drug-induced liver damage include the damage of the drug itself to the liver and the idiosyncratic response of the body to the drug, so the former is often referred to as predictable damage, while the latter is mostly unpredictable. The clinical manifestations of drug-induced hepatitis vary widely and can be acute or chronic. Acute drug-induced hepatitis is mostly characterized by fever, malaise, darkened urine, itchy skin, hepatomegaly, and abnormal liver function, etc. In severe cases, fulminant liver failure may occur, with massive necrosis of liver cells, and the patient may die within one to two weeks. About 10-20% of fulminant liver failure is caused by drugs, and the morbidity and mortality rate is up to 50% or more. Chronic drug-related hepatitis starts slowly, often accompanied by hepatosplenomegaly, and some patients may develop extrahepatic manifestations such as arthritis, kidney damage, skin mucosal lesions, etc. If the drug is not stopped in time for treatment, liver failure or cirrhosis may develop. Treatment: Immediately stop the use of drugs damaging to the liver.