If the tumor metastasizes to the spine and bones, it will cause back pain in patients with advanced rectal cancer. When rectal cancer metastasizes to the spine, back pain can also be the first symptom of patients. When it develops to the later stage, patients will experience weakness of lower limbs, urinary and fecal incontinence, and in serious cases, paraplegia, etc. If timely treatment is not carried out, patients’ lives will be endangered. If the tumor compresses the spinal cord, dexamethasone can be given to reduce the edema and neurological damage of the spinal cord; local radiotherapy or local bone cement treatment can also be given; surgical resection treatment can also be given; internal medicine can give oxycodone extended-release tablets and other analgesic drugs for symptomatic treatment. The pain can also be treated with surgical resection.