A wart on your hand is caused by a human papilloma virus infection. A wart is also known as a “verruca”. Warts are benign growths on the surface of the skin caused by human papillomavirus (HPV) infection, which can occur in various parts of the body and are contagious, and can be contracted through direct contact with the patient’s skin or indirect contact with contaminated objects, etc. Humans are the original hosts and reservoirs of HPV. Humans are the original host and reservoir of HPV. If HPV escapes the human immune response, it becomes a human pathogen. When there is a break in the skin, HPV can invade into the epithelial cells, where the virus replicates and multiplies, causing abnormal proliferation and differentiation of the epithelial cells and the appearance of redundant organisms on the skin. In addition, low immunity (e.g. malignant lymphoma, organ transplant recipients), sharing personal items such as towels with infected people, frequent soaking of hands in water, frequent nail biting, and working in meat processing are all risk factors for the disease. It is recommended that patients go to the dermatology department of regular hospitals, and under the guidance of the doctor, combine with their own conditions to choose the appropriate treatment plan.