Patients with anemia that progresses to a severe level are treated with blood transfusions, and depending on the severity of the anemia, blood products need to be transfused according to the clinical presentation. Blood transfusion has necessity, specificity, and risk. After blood input, the human body will have adverse transfusion reactions, and blood transfusion can lead to disseminated diseases, so anemia transfusion has certain risks. At present, medical treatment and blood product management have reduced the risk to a very low medical level, and clinical treatment will not cause great impact on the body as long as it is timely. The main risk is the input of infectious diseases, including AIDS, syphilis, hepatitis C and hepatitis B. However, the blood products provided by the blood product management centers are very safe, and the pre-transfusion testing and donor health testing are very standardized, so there are risks in blood transfusion, but don’t be afraid, the risk is very low and there is no need to panic.