Calcification of small nodules on the lungs is mostly indicative of imaging changes left by patients with previous tuberculosis infection. After standardized anti-tuberculosis treatment, tuberculosis patients have incomplete absorption of lung lesions to form polymorphic changes such as proliferation, nodules, calcification, fibrosis, and pleural thickening, with calcification being the most common. Once calcification of small nodules appears, it is mostly benign, not infectious, and does not require drug treatment. It only requires dynamic annual high-resolution CT of the chest to assess the size and stability of calcified nodules. Calcification of small nodules in the upper lobe of the lung is also seen in people with pneumonia, long-term smoking, and dust operations, including masons and coal mines. These people are prone to the formation of calcified nodules on the lungs after prolonged exposure to dust, which manifests as nodular calcification because of the high amount of silica in the dust. Chest imaging CT can clearly indicate the difference between calcified and proliferative foci, and no special treatment is needed.