Many diseases have an impact on the growth of children, only the degree of its impact may be light or heavy. In the prevention of disease is divided into these categories of diseases to pay attention to: 1, the most common reason is the endocrine reasons, endocrine diseases directly affect the child’s height. Endocrine causes such as growth hormone deficiency, hypothyroidism and other diseases; 2, there are some chronic diseases such as asthma, hepatitis B, hepatitis, recurrent respiratory infections, recurrent allergic diseases, the growth of the child are affected; 3, nutritional diseases, such as malnutrition in small children, picky eaters, partiality, iron-deficiency anemia, zinc deficiency diseases, calcium deficiency diseases, Vitamin D deficiency nutritional diseases, may have an impact on growth; 4, there is a class of diseases that parents may not be so easy to pay attention to is the child’s psychological disorders, such as mood disorders, poor mood, etc. on the child’s growth also has a great impact; 5, especially to remind parents and friends to pay attention to one point, that is, for a short girl, we must be wary of chromosomal disorders and genetic metabolic disorders. The first thing to do is to make sure that you have a good understanding of your child’s condition. For example, the first step in the examination of girls with short stature is congenital ovarian hypoplasia. The clinical manifestations of this disease can vary in severity, with mild cases being atypical, but it is important to screen for this disease early. Congenital ovarian hypoplasia is also characterized by a chromosome of 45XO, lacking an X sex chromosome. The main effects of this disease on girls are shortness and sexual dysplasia, because this disease not only affects height, but also affects puberty and fertility, so parents should also pay special attention to this type of disease.