Cryptococcus causes mainly central nervous system, pulmonary and cutaneous lesions, which can be life-threatening in severe cases. Disseminated lesions can also occur in the ends of long bones, joints, liver, spleen, kidneys, heart, testes, prostate, and other organs. Typically, affected tissues contain peptide-like yeast cysts, which are formed by the accumulation of polysaccharides in the cryptococcal cyst membrane, but have only mild or no acute inflammatory changes. In severe cases, sepsis may occur and spread to all organs of the body or even cause death. So how can Cryptococcus cysticercus polysaccharide buildup be prevented? Take a look below. Immunologically unimpaired patients with only focal lung involvement, confirmed normal cerebrospinal fluid parameters, negative cerebrospinal fluid and urine cultures, and no signs of skin, bone, or other extrapulmonary tissue lesions may not require treatment. In the absence of meningitis, limited lesions of skin, bone, and other sites require systemic antifungal therapy, but the optimal treatment regimen has not been determined from comparative trials. Amphotericin B in combination with flucytosine or amphotericin B alone has been shown to be effective in most cases, but successful treatment with oral amphotericin B has been reported recently. 1. Active treatment of the underlying disease and enhancement of the patient’s organism immunity. 2, long-term application of immunosuppressants should be actively given prophylactic antifungal drugs, or immune enhancers. 3.Strengthen protective isolation for critically ill patients, pay attention to keep the environment clean and dry, and control the flow of people in and out. 4.Actively treat fungal infection of skin mucosa and prevent hematogenous dissemination.