The most common manifestation of the decline of ovarian function is premenopausal syndrome, originally called menopausal syndrome, with the following specific manifestations: 1. Recent symptoms: including menstrual disorders, because the ovaries cannot ovulate, patients may experience disorders of the menstrual cycle, and may also experience disorders of the menstrual period, which may result in a gradual decrease in menstruation or even amenorrhea; the second is the functional symptoms of the autonomic nerves, like dizziness, headache, and The second is autonomic symptoms, such as dizziness, headache, insomnia, etc.; there are also psychoneurological symptoms, some patients may be irritable and easily provoked. Other people may be the opposite, prone to depression, depression, mood swings, not able to control their emotions, some people may even experience memory loss; another is afternoon hot flashes, mainly related to the reduction of estrogen; 2, distant symptoms: including symptoms of the reproductive tract, such as dryness during sexual intercourse, repeated inflammation of the vagina; or the emergence of Some patients may develop Alzheimer’s disease, commonly known as dementia, which is significantly more common in elderly women than in elderly men, and is also related to the decrease in estrogen levels in postmenopausal women.