Kidney Failure Ning and Urotoxic Clear are two kinds of Chinese patent medicines used in the treatment of chronic renal insufficiency, both of them have the following similarities and differences: First, the composition of Kidney Failure Ning is composed of Prince’s ginseng, Huang Lian, Fa Han Xia, Chen Pi, Fu Ling, Da Huang, Dan Shen, Niubizi, Safflower and Licorice, while Urotoxic Clear is composed of 16 Chinese medicines, including Da Huang, Huang Qi, Bai Zhu, Sang Bai Pi, Fu Ling, Chuan Xiong and Dan Shen. Both of them are used in the treatment of chronic renal insufficiency to reduce serum creatinine and stabilize renal function. Third, urushiol has the unique effect of improving renal anemia, raising blood calcium and lowering blood phosphorus.