In mild cases of mitral regurgitation, the life expectancy of the patient is usually not affected, whereas in severe cases, the life expectancy varies from about 5 years. Mitral regurgitation is caused by incomplete closure of the mitral valve resulting in blood flowing back into the left atrium and can be seen in rheumatic heart disease, infective endocarditis, and mitral tendon rupture. Patients with mild mitral regurgitation have no obvious symptoms or exhibit mild weakness, chest tightness, panic, shortness of breath, etc. They should avoid straining and overstress in life, which usually does not affect the life expectancy of patients. The success rate is higher if there are no other complications after surgery, and it does not affect the patient’s life expectancy. Severe mitral regurgitation can cause heart failure and has a poor prognosis, with a life expectancy of about 5 years. Patients with mitral regurgitation should go to the hospital regularly for review and active treatment of the primary disease, and if symptoms such as chest tightness and wheezing occur, they should go to the cardiology department for treatment in a timely manner.