Upper abdominal distension may be related to digestive system diseases, or may be related to certain drug stimulation or poor lifestyle. 1. Digestive system diseases: peptic ulcer, acute and chronic gastritis, cholecystitis, gallbladder stones, pancreatitis, appendicitis and other diseases can lead to epigastric distension symptoms. 2. Drug stimulation: taking stimulant drugs such as antibiotics on an empty stomach can also cause epigastric distension. 3. Poor lifestyle: excessive stress, frequent late nights, irregular work and rest, irregular diet, etc., can lead to digestive disorders, epigastric pain. There are many other causes of epigastric pain, such as depression, anxiety, irritable bowel syndrome, menopausal syndrome and other functional diseases. If the symptoms continue to be unrelieved or accompanied by other symptoms, it is recommended to go to the hospital in a timely manner, under the guidance of a professional physician to clarify the cause of the disease.