The preferred treatment for penicillin-resistant Streptococcus pneumoniae infections is cefotaxime or ceftriaxone, but also neoquinolones such as moxifloxacin and sparfloxacin, and for very serious infections, vancomycin or the addition of rifampicin is required. What is penicillin-resistant Streptococcus pneumoniae? There are currently six species of Streptococcus pneumoniae in the world, of which bpb2b on Streptococcus pneumoniae is one of the most important binding sites, and if this site mutates, the streptococcus will become resistant. Streptococcus pneumoniae is the most common causative agent of community-acquired pneumonia. The incidence of drug-resistant bacteria in China is currently around 4%, which is significantly lower than abroad, that is, it belongs to the middle level in Asia, so among the pathogens of acquired community lung infections, infection by drug-resistant Streptococcus pneumoniae does not constitute a serious threat.