Before really recognizing the seriousness of cranial defects, many people think that cranial defects seem to affect only the appearance, and there should not be too big a problem as far as health is concerned. But this idea is obviously wrong, we must know that the skull is a layer of protection for the brain, if the skull defect, the intracranial tissues do not have the necessary protection, at any time may be dangerous. In the clinic, many patients are caused by cranial defects that lead to neurological damage, and a series of uncomfortable symptoms appear on the body, such as headache, dizziness, anxiety, depression, sleep disorders, lack of concentration, memory loss, and even neurological dysfunction, etc. This will have an impact on the patient’s life and work. Can a cranial defect be left unrepaired? Obviously, it is not possible to leave large cranial defects unrepaired for a long period of time, and in serious cases, it will lead to atrophy and cystic degeneration of brain tissues, so patients should realize the seriousness of the problem and go to the hospital for cranial repair surgery before it is too late. Moreover, the safety of cranial repair surgery is still very high, patients do not need to worry too much, as long as the material is well selected, coupled with the doctor’s mature technology, the operation can still be a good recovery. At present, there are many kinds of cranial bone repair materials, among which titanium mesh material and peek material are attracting much attention, but after many times of clinical verification, titanium mesh material still has certain deficiencies, compared with peek material is more reliable. peek material is a new type of special polymer material, which makes up for the deficiencies of the titanium mesh material, and the effect of the postoperative period is very ideal. We have successfully used peek material to carry out surgery, and they also continue to carry out technical upgrades and material optimization design, comprehensively carried out peek cranioplasty, the postoperative effect is very natural and beautiful, highly recognized by the medical.