There are many types of perianal itching creams, and you need to choose the appropriate cream based on the cause. Perianal itching is mostly caused by perianal skin eczema. Treatment of perianal eczema, in addition to cleaning the anus, can be used under the guidance of a physician tretinoin econazole cream, hydrocortisone butyrate ointment and other ointments containing glucocorticoids, which can alleviate the symptoms of itching. If the perianal skin has broken skin and fluid due to bacterial infection, folliculitis, etc., antibiotic-containing ointments such as mupirocin cream can be used for treatment. And fungal infections of perianal skin can be treated with ointments such as ketoconazole ointment and miconazole ointment. In addition, if the perianal itching is caused by hemorrhoids, rectal mucosal prolapse and some other anal diseases, you can use some commonly used topical medications, such as Longzhu ointment, Ma Yinglong musk hemorrhoid ointment, Chlorhexidine hemorrhoid suppositories and other medications to relieve itching symptoms. In short, regardless of the cause of perianal itching, it is recommended to the regular hospital anorectal consultation, diagnosed by a professional doctor and then use the appropriate medication.