Positive carbon 14 breath test indicates the presence of H. pylori infection, and its severity depends on the occurrence of serious lesions, such as intestinal epithelial hyperplasia, cancer, etc. If it is only H. pylori infection, it is not considered serious, but if it is combined with the above lesions, it is more serious. Carbon 14 breath test is a test to detect H. pylori, positive indicates the presence of H. pylori infection, once diagnosed with H. pylori infection need to be treated with quadruple therapy under the guidance of a doctor, i.e., two antibiotics combined with a proton pump inhibitor, a bismuth agent, such as metronidazole, amoxicillin combined with pantoprazole, bismuth potassium citrate. Patients with simple H. pylori infection can effectively eradicate H. pylori after standardized treatment, which is generally not serious; however, it is more serious when combined with chronic gastritis with intestinal epithelial hyperplasia or even cancer. Patients with a positive carbon 14 breath test are advised to go to the hospital and ask the doctor to make a judgment.