Acute pancreatitis caused or induced by hyperlipidemia should first be systematically treated with symptomatic therapy such as anti-infective therapy, intravenous fluid supplementation, adjustment of the stability of the internal environment, and lipid-lowering. During the treatment, the changes of blood routine, amylase and biochemical indexes should be monitored to prevent ionic disorder and acid-base imbalance. During rehydration, the daily intake of basic sugar, trace elements and vitamins should be ensured, and the patient should be instructed to move out of bed to promote the recovery of intestinal peristalsis. If the patient is combined with anemia and hypoproteinemia, intravenous supplementation of erythrocytes, plasma, and human albumin can also be used to increase the colloid osmotic pressure of plasma and reduce the generation of fluid in the abdominal cavity. And if the complication of limited peritonitis, abdominal abscess formation, need to be treated with surgical incision and drainage.